Kết quả ATP Madrid - Vòng 1/64
| Cặp đấu | Tỉ số |
| Dominic Koepfer - Roberto Carballes Baena | |
| Alex Michelsen - Joao Fonseca (WC) | |
| Darwin Blanch (WC) 0-1 Rafael Nadal | 1-6 (đang diễn ra) |
| Albert Ramos-Vinolas (Q) 0-2 Pavel Kotov | 3-6; 4-6 |
| Aleksandar Kovacevic (Q) - Hamad Medjedovic (Q) | |
| Zhang Zhizhen 0-2 Miomir Kecmanovic | 3-6; 2-6 |
| Yannick Hanfmann 0-2 Jakub Mensik | 4-6; 6-7 |
| Daniel Galan 1-2 Roberto Bautista-Agut (LL) | 6-7; 6-4; 1-6 |
| Max Purcell 2-1 Marcos Giron | 4-6; 6-4; 7-6 |
| Christopher O'Connell 0-2 Matteo Arnaldi | 4-6; 1-6 |
| Dusan Lajovic 0-2 Thiago Monteiro (Q) | 4-6; 3-6 |
| Richard Gasquet (Q) 0-2 Lorenzo Sonego | 2-6; 5-7 |
| Alejandro Tabilo 1-2 Flavio Cobolli | 7-5; 4-6; 4-6 |
| Yoshihito Nishioka 1-2 Felix-Auger Aliassime | 6-4; 1-6; 4-6 |
| Tomas Machac 2-1 Emil Ruusuvuori | 6-4; 1-6; 6-2 |
| Pedro Cachin 2-0 Sebastian Ofner | 6-3; 6-3 |
Kết quả WTA Madrid - Vòng 1/32
| Cặp đấu | Tỉ số |
| Anna Karolina Schmiedlova - Ons Jabeur [8] | |
| Leylah Fernandez [32] - Anastasia Potapova | |
| Elise Mertens [28] - Sloane Stephens | |
| Maria Lourdes Carle (Q) - Veronika Kudermetova [17] | |
| Beatriz Haddad Maia [11] 2-0 Sara Errani (Q) | 6-3; 6-2 |
| Coco Gauff [3] 2-0 Arantxa Rus | 6-0; 6-0 |
| Alexandra Eala (WC) 1-2 Sorana Cirstea [27] | 3-6; 7-6; 4-6 |
| Nadia Podoroska (ALT) 0-2 Emma Navarro [19] | 2-6; 1-6 |
| Jelena Ostapenko [9] 2-0 Jessica Bouzas Maneiro (Q) | 6-3; 6-1 |
| Naomi Osaka (PR) 1-2 Liudmila Samsonova [15] | 2-6; 6-4; 5-7 |
| Emiliana Arango (Q) 1-2 Dayana Yastremska [31] | 6-0; 5-7; 4-6 |
| Donna Vekic 0-2 Maria Sakkari [5] | 3-6; 2-6 |
| Sara Sorribes Tormo 2-0 Elina Svitolina [16] | 6-3; 7-5 |
| Madison Keys [18] 2-0 Irina-Camelia Begu (PR) | 7-6; 7-6 |
| Victoria Azarenka [23] 2-0 Tatjana Maria | 6-3; 6-1 |
